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Torin 2
Price range: 56 CAD through 1,525 CAD
Products Details
Product Description
– Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 28 nM/35 nM/118 nM, respectively.
Web ID
– T6100
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H15F3N4O
Citations
– 1. Jiang X, Liu K, Jiang H, et al.SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.Cell Reports.2023, 42(1): 111984.
References
– Liu Q, et al. J Med Chem, 2011, 54(5), 1473-1480.
CAS Number
– 1223001-51-1
Molecular Weight
– C24H15F3N4O
Compound Purity
– 0.9947
SMILES
– Nc1ccc(cn1)-c1ccc2ncc3ccc(=O)n(-c4cccc(c4)C(F)(F)F)c3c2c1
Pathway
– Apoptosis|||DNA Damage/DNA Repair|||Autophagy|||PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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