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E-64
Price range: 50 CAD through 1,331 CAD
Products Details
Product Description
– E-64 (Proteinase inhibitor E 64) is an irreversible and specific inhibitor of cysteine proteases, exhibiting an IC50 of 9 nM for papain.
Web ID
– T6037
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H27N5O5
Citations
– 1. Guan X N, Zhang T, Yang T, et al. Covalent Sortase A Inhibitor ML346 Prevents Staphylococcus aureus Infection of Galleria mellonella. RSC Medicinal Chemistry. 2022
2. Jiang T Y, Pan Y F, Wan Z H, et al. PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma. Science Translational Medicine. 2020, 12(562).
3. Zhang B, Chen Z. Screening of cathepsin B inhibitors in traditional Chinese medicine by capillary electrophoresis with immobilized enzyme microreactor. Journal of Pharmaceutical and Biomedical Analysis. 2019: 112811
4. Thuduhena A C, Abu-Bakar N, Hamzah S N.Effects of Ellagic Acid on Hemoglobin Ingestion, Transport, and Digestion in the Digestive Vacuole of Plasmodium falciparum.Journal of Microscopy and Ultrastructure.10.4103.
References
– Matsumoto K, et al. Biopolymers. 1999, 51(1), 99-107.
CAS Number
– 66701-25-5
Molecular Weight
– C15H27N5O5
Compound Purity
– 0.9995
SMILES
– CC(C)CC(NC(=O)C1OC1C(O)=O)C(=O)NCCCCN=C(N)N
Pathway
– Autophagy|||Proteases/Proteasome|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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