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AV123
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor with an IC50 of 12.12 μM. It blocks TNF-α-induced necroptosis with an EC50 of 1.7 μM, but not apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart, and kidney, inflammatory diseases, neurodegenerative diseases, and infectious diseases [1].
Web ID
– T60316
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H14N4O2
CAS Number
– 233605-81-7
Molecular Weight
– C11H14N4O2
SMILES
– N(=O)(=O)C=1C=C2C(N=C(NCCCC)N2)=CC1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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