MSC-4106

SKU T60148-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 155 CAD through 2,752 CAD

Products Details

Product Description

– MSC-4106, an orally active and potent YAP/TAZ-TEAD inhibitor, disrupts TEAD1 and TEAD3 auto-palmitoylation and demonstrates significant efficacy in the NCI-H226 tumor xenograft model [1].

Web ID

– T60148

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H12F3N3O2

References

– Timo Heinrich, et al. Optimization of TEAD P-site binding fragment hit into in vivo active lead MSC-4106. J. Med. Chem. 2022, 65, 13, 9206–9229.

CAS Number

– 2738542-58-8

Molecular Weight

– C18H12F3N3O2

Compound Purity

– 1

SMILES

– Cn1cc2c3cc(ccc3n(-c3ccc(cc3)C(F)(F)F)c2n1)C(O)=O

Pathway

– Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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