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Romidepsin
Price range: 149 CAD through 2,528 CAD
Products Details
Product Description
– Romidepsin (FR 901228) is an HDAC inhibitor that inhibits HDAC1/2/4/6 (IC50=36/47/510/1400 nM). Romidepsin has antitumor activity and can be used for the treatment of peripheral T-cell lymphoma and cutaneous T-cell lymphoma.
Web ID
– T6006
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H36N4O6S2
Citations
– 1. Zhao Y, Guo Y, Sun M, et al. Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage. Journal of Bone and Mineral Metabolism. 2022: 1-13.
2. Sun L, Wan A H, Yan S, et al.A multidimensional platform of patient-derived tumors identifies drug susceptibilities for clinical lenvatinib resistance.Acta Pharmaceutica Sinica B.2023
References
– Valdez BC, et al. Romidepsin targets multiple survival signaling pathways in malignant T cells. Blood Cancer J. 2015 Oct 16;5(10):e357.
CAS Number
– 128517-07-7
Molecular Weight
– C24H36N4O6S2
Compound Purity
– 0.9994
SMILES
– [H][C@]12CSSCCC=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N1)OC(=O)[C@@H](NC(=O)C(NC2=O)=CC)C(C)C
Pathway
– DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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