YS-370

SKU T60009-1 mg Category Brand:

Price range: 93 CAD through 1,229 CAD

Products Details

Product Description

– YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.

Web ID

– T60009

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C37H35BrN4O3

References

– Yuan S, et al. Discovery of New 4-Indolyl Quinazoline Derivatives as Highly Potent and Orally Bioavailable P-Glycoprotein Inhibitors. J Med Chem. 2021;64(19):14895-14911.

CAS Number

– 2470908-79-1

Molecular Weight

– C37H35BrN4O3

Compound Purity

– 0.975

SMILES

– COc1cc2ncnc(-c3c(-c4ccccc4)n(Cc4ccccc4Br)c4ccccc34)c2cc1OCCCN1CCOCC1

Pathway

– Neuroscience|||Membrane transporter/Ion channel

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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