Belvarafenib
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Belvarafenib

SKU T5634-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 611 CAD

Products Details

Product Description

– Belvarafenib (HM95573) is a potent pan-RAF inhibitor with antitumor activity and inhibits B-RAF, B-RAFv600E, and C-RAF with IC50 values of 56, 7, and 5 nM.

Web ID

– T5634

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H16ClFN6OS

Citations

– 1. Li W, Shi X, Tan C, et al.Plasma membrane-associated ARAF condensates fuel RAS-related cancer drug resistance.Nature Chemical Biology.2025: 1-12.

References

– Son J B , Jung S H , Choi Ii W , et al. Thieno[3,2-d]pyrimidine derivatives having inhibitory activity on protein kinases[J]. 2015.

CAS Number

– 1446113-23-0

Molecular Weight

– C23H16ClFN6OS

Compound Purity

– ≥98%

SMILES

– Cc1ccc2c(Nc3cccc(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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