ULK-101
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ULK-101

SKU T5403-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 181 CAD through 3,184 CAD

Products Details

Product Description

– ULK-101 is a potent and selective inhibitor of ULK1 (IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.

Web ID

– T5403

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H16F4N4OS

Citations

– 1. Xia Z, Zhang X, Liu P, et al. GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner. Cell Death & Disease. 2021, 12(1): 1-11.

References

– Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.

CAS Number

– 2443816-45-1

Molecular Weight

– C22H16F4N4OS

Compound Purity

– 0.9966

SMILES

– Fc1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)N[C@@H](C1CC1)C(F)(F)F

Pathway

– Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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