azd1390
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azd1390

SKU T5175-1 mg Category Brand:

Price range: 128 CAD through 1,275 CAD

Products Details

Product Description

– AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10,000-fold selectivity over closely related members of the PIKK family of enzymes.

Web ID

– T5175

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H32FN5O2

References

– Durant ST, et al. The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models. Sci Adv. 2018 Jun 20;4(6):eaat1719.

CAS Number

– 2089288-03-7

Molecular Weight

– C27H32FN5O2

Compound Purity

– 0.9747

SMILES

– CC(C)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN3CCCCC3)nc2)n(C)c1=O

Pathway

– DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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