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Tofogliflozin (hydrate)
Price range: 61 CAD through 2,288 CAD
Products Details
Product Description
– Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2, with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2, respectively.
Web ID
– T5016
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H28O7
References
– Ishibashi Y, et al. Tofogliflozin, A Highly Selective Inhibitor of SGLT2 Blocks Proinflammatory and Proapoptotic Effects of Glucose Overload on Proximal Tubular Cells Partly by Suppressing Oxidative Stress Generation. Horm Metab Res. 2016 Mar;48(3):191-5.
CAS Number
– 1201913-82-7
Molecular Weight
– C22H28O7
Compound Purity
– 0.9702
SMILES
– O.CCc1ccc(Cc2ccc3CO[C@]4(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c3c2)cc1
Pathway
– Immunology/Inflammation|||GPCR/G Protein|||NF-κB|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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