(-)-Alkannin
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(-)-Alkannin

SKU T4958-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 315 CAD

Products Details

Product Description

– (-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns. It can suppress the cell viability, adhesion, invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.

Web ID

– T4958

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H16O5

Citations

– 1. Zhang Z Z, Wen C H, Jia M, et al. Alkannin exerts antitumor properties in cutaneous squamous cell carcinoma by inducing apoptosis and shifting the M1/M2 polarization of tumor‐associated macrophages by upregulating PTEN. The Kaohsiung Journal of Medical Sciences. 2022 2. Xu J, Wang Q, Leung E L H, et al. Compound C620-0696, a new potent inhibitor targeting BPTF, the chromatin-remodeling factor in non-small-cell lung cancer. Frontiers of Medicine. 2020, 14(1): 60-67.

References

– Takano-Ohmuro H , Yoshida L S , Yuda Y , et al. Shikonin inhibits IgE-mediated histamine release by human basophils and Syk kinase activity[J]. Inflammation Research, 2008, 57(10):484-488.

CAS Number

– 517-88-4

Molecular Weight

– C16H16O5

Compound Purity

– 0.9828

SMILES

– CC(C)=CC[C@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O

Pathway

– Apoptosis|||PI3K/Akt/mTOR signaling

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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