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4-Octyl itaconate
Price range: 48 CAD through 93 CAD
Products Details
Product Description
– 4-Octyl Itaconate, a cell-permeable derivative of Itaconate, is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 and inhibits phosphorylation of STING.
Web ID
– T4580
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H22O4
Citations
– 1. Wang S J, Ye W, Li W Y, et al.Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.Journal of Ethnopharmacology.2022: 116053.
2. Wang Z, Cui L, Lin Y, et al.Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity.The EMBO Journal.2024: 1-18.
References
– Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAPNature. 2018 Apr 5;556(7699):113-117.
CAS Number
– 3133-16-2
Molecular Weight
– C13H22O4
Compound Purity
– 0.9994
SMILES
– C(CC(C(O)=O)=C)(OCCCCCCCC)=O
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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