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SPDB
Price range: 48 CAD through 573 CAD
Products Details
Product Description
– SPDB is a degradable ADC linker that can be used to synthesize antibody-drug conjugates. SPDB is a small fragment attached to the DM4 conjugate and conjugated to the antibody using a disulfide bond.
Web ID
– T4346
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H14N2O4S2
References
– Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing. Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.
CAS Number
– 115088-06-7
Molecular Weight
– C13H14N2O4S2
Compound Purity
– 0.9987
SMILES
– O=C(CCCSSc1ccccn1)ON1C(=O)CCC1=O
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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