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Products Details
Product Description
– 12(S)-HHT (12(S)-HHTrE), a fatty acid produced via the arachidonic acid metabolic pathway of cyclooxygenase (COX), is an endogenous ligand and agonist of BLT2, and the 12(S)-HHT/BLT2 axis plays a role in the maintenance of homeostatic aspects of epithelial tissues and in inflammatory responses. 12(S)-HHT inhibits the p38 MAPK/NF-κB pathway through upregulation of MKP-1, leading to reduced IL-6 synthesis in UVB-irradiated HaCaT cells.
Web ID
– T41365
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H28O3
CAS Number
– 54397-84-1
Molecular Weight
– C17H28O3
SMILES
– [C@@H](/C=C/C=C/C/C=CCCCC(O)=O)(CCCCC)O
Pathway
– Metabolism
Product type
– Natural Product
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