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3-TYP
Price range: 53 CAD through 1,093 CAD
Products Details
Product Description
– 3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.
Web ID
– T4108
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C7H6N4
Citations
– 1. Lahiri T, Brambilla L, Andrade J, et al. Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer. Molecular Oncology. 2021 May;15(5):1432-1449. doi: 10.1002/1878-0261.12928. Epub 2021 Apr 10.
2. Zhang Y, Gao F, Gong H, et al.Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation.Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.2023: 166638.
3. Xue K H, Jiang Y F, Bai J Y, et al.Melatonin suppresses Akt/mTOR/S6K activity, induces cell apoptosis, and synergistically inhibits cell growth with sunitinib in renal carcinoma cells via reversing Warburg effect.Redox Report.2023, 28(1): 2251234.
4. Shi Y, Xing L, Zheng R, et al.Butyrate attenuates high-fat diet induced glomerulopathy through GPR43-Sirt3 pathway.The British journal of nutrition.2024: 1-27.
References
– Pi H, et al. SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin. Autophagy. 2015;11(7):1037-51
CAS Number
– 120241-79-4
Molecular Weight
– C7H6N4
Compound Purity
– 0.9916
SMILES
– c1[nH]nnc1-c1cccnc1
Pathway
– DNA Damage/DNA Repair|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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