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Products Details
Product Description
– ADTL-SA1215 is a selective SIRT3 activator with SIRT3 deacetylase activity that inhibits the proliferation and migration of human breast cancer MDA-MB-231 cells through the SIRT3-driven autophagy/mitochondrial autophagy signaling pathway, and can be used in the study of triple negative breast cancer.
Web ID
– T40891
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H29I2NO3
References
– Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14192-14216.
CAS Number
– 782387-91-1
Molecular Weight
– C26H29I2NO3
Compound Purity
– 0.9923
SMILES
– CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCCN2CCCC2)c(I)c1
Pathway
– Chromatin/Epigenetic|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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