Thio-ITP

SKU T40359-5 mg Category Brand:

1,552 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– Thio-ITP, also known as 6-Thioinosine 5′-triphosphate, is a competitive inhibitor of RNA polymerase activity. It exhibits a strong apparent affinity towards the polymerases, with Ki values of 40.9 μM for RNA polymerase I and 38.0 μM for RNA polymerase II.

Web ID

– T40359

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H15N4O13P3S

References

– Kawahata RT, Chuang LF, Holmberg CA, Osburn BI, Chuang RY. Inhibition of human lymphoma DNA-dependent RNA polymerase activity by 6-mercaptopurine ribonucleoside triphosphate. Cancer Res. 1983 Aug;43(8):3655-9.

CAS Number

– 27652-34-2

Molecular Weight

– C10H15N4O13P3S

SMILES

– O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]cnc2=S

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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