(Iso)-MS4322

SKU T40233-1 mg Category Brand:

Price range: 782 CAD through 6,800 CAD

Products Details

Product Description

– (Iso)-MS4322 ((Iso)-YS43-22) is a selective and potent protein arginine methyltransferase 5 (PRMT5) degrader with potential anticancer activity that effectively reduces PRMT5 protein levels in MCF-7 cells and inhibits the growth of a wide range of cancer cells.

Web ID

– T40233

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C55H76N10O12S

References

– Shen Y, et al. Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. J Med Chem. 2020 Sep 10;63(17):9977-9989.

CAS Number

– 2601727-80-2

Molecular Weight

– C55H76N10O12S

Compound Purity

– 0.9905

SMILES

– C[C@@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](NC(=O)COCCOCCOCCOCCOCC(=O)N1CC(C1)Nc1cc(ncn1)C(=O)NC[C@H](O)CN1CCc2ccccc2C1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

Pathway

– Chromatin/Epigenetic|||PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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