QS11
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QS11

SKU T4022-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 784 CAD

Products Details

Product Description

– QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.

Web ID

– T4022

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H33N5O2

Citations

– 1. Song S, Guo X, Zhang Z, et al.A universal strategy of facilitating intracellular delivery of nanomedicines based on tuning ARF6 GTPase to its GTP-bound form.Nano Today.2023, 51: 101888.

References

– Emre N., et al. A chemical approach to stem cell biology. Curr Opin Chem Biol. 2007 Jun;11(3):252-8.

CAS Number

– 944328-88-5

Molecular Weight

– C36H33N5O2

Compound Purity

– 0.9859

SMILES

– OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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