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Bcl-2-IN-2
1,552 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Bcl-2-IN-2 is a highly potent and selective inhibitor targeting Bcl-2 and Bcl-xL, displaying an IC50 value of 0.034 nM against Bcl-2 and 43 nM against Bcl-xL, demonstrating over 1000-fold selectivity for Bcl-2 compared to Bcl-xL.
Web ID
– T39961
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C48H57N7O7S
References
– Yunhang GUO, et al. Bcl-2 INHIBITORS. WO2019210828A1.
CAS Number
– 2383085-86-5
Molecular Weight
– C48H57N7O7S
SMILES
– CCc1ccccc1[C@@H]1CCCN1C1CC2(C1)CCN(CC2)c1ccc(C(=O)NS(=O)(=O)c2ccc(NC[C@H]3CC[C@](C)(O)CC3)c(c2)N(=O)=O)c(Oc2cnc3[nH]ccc3c2)c1 |wU:8.8,41.46,wD:38.41,41.45,(10.07,9.11,;9.75,10.61,;10.9,11.64,;12.36,11.17,;13.5,12.2,;13.18,13.7,;11.72,14.18,;10.58,13.15,;9.11,13.63,;8.64,15.09,;7.1,15.09,;6.62,13.63,;7.87,12.72,;7.87,11.18,;8.95,10.09,;7.87,9,;6.78,10.09,;9.2,8.23,;9.2,6.69,;7.87,5.92,;6.53,6.69,;6.53,8.23,;7.87,4.38,;9.2,3.61,;9.2,2.07,;7.87,1.3,;7.87,-.24,;6.53,-1.01,;9.2,-1.01,;10.53,-.24,;9.76,1.1,;11.3,-1.57,;11.87,.53,;13.2,-.24,;14.53,.53,;14.53,2.07,;15.87,2.84,;15.87,4.38,;17.2,5.15,;18.53,4.38,;19.87,5.15,;19.87,6.69,;20.4,8.14,;21.38,6.43,;18.53,7.46,;17.2,6.69,;13.2,2.84,;11.87,2.07,;13.2,4.38,;14.53,5.15,;11.87,5.15,;6.53,2.07,;5.2,1.3,;3.86,2.07,;3.86,3.61,;2.53,4.38,;1.2,3.61,;-.27,4.09,;-1.17,2.84,;-.27,1.6,;1.2,2.07,;2.53,1.3,;6.53,3.61,)|
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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