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MW-150 hydrochloride
2,432 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a potent and selective inhibitor of p38α MAPK with a Ki value of 101 nM. It exhibits excellent CNS penetration and oral bioavailability, and effectively suppresses the phosphorylation of MK2, a substrate of endogenous p38α MAPK, in activated glial cells.
Web ID
– T39343
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H24ClN5
References
– Roy SM, et al. Targeting human central nervous system protein kinases: An isoform selective p38αMAPK inhibitor that attenuates disease progression in Alzheimer’s disease mouse models. ACS Chem Neurosci. 2015 Apr 15;6(4):666-80.
CAS Number
– 1923773-01-6
Molecular Weight
– C24H24ClN5
SMILES
– Cl.CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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