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MC-betaglucuronide-MMAE-1
Products Details
Product Description
– MC-betaglucuronide-MMAE-1 is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), utilizing MMAE (a tubulin polymerization inhibitor) connected via the cleavable ADC linker MC-betaglucuronide.
Web ID
– T39164
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C66H98N8O20
References
– Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.
CAS Number
– 1703778-92-0
Molecular Weight
– C66H98N8O20
SMILES
– CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)c(NC(=O)CCNC(=O)CCCCCN2C(=O)C=CC2=O)c1)C(C)C
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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