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Zanamivir-13C,15N2
2,438 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intranasal zanamivir administration at 0.4 mg/kg twice daily reduces mortality and viral titers in lung homogenates of mice infected with influenza.
Web ID
– T38118
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C12H20N4O7
References
– Elliott, M.Zanamivir: From drug design to the clinicPhilos. Trans. R. Soc. Lond. B Biol Sci.356(1416)1885-1893(2001)
CAS Number
– 1276528-62-1
Molecular Weight
– C12H20N4O7
SMILES
– [H][C@]1(OC(=C[C@H](N[13C]([15NH2])=[15NH])[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO |c:3|
Product type
– Isotope products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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