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Products Details
Product Description
– Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2α and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 μM and demonstrates an EC50 value of 0.80 μM in an in vitro functional assay. Designed to enhance corneal absorption, AL 6598 produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 μg dose given twice daily.
Web ID
– T38113
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H39ClO5
CAS Number
– 170291-06-2
Molecular Weight
– C23H39ClO5
SMILES
– C(C[C@@H](O)C1CCCCC1)[C@@H]2[C@@H](C/C=CCOCC(OC(C)C)=O)[C@H](Cl)C[C@H]2O
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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