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Products Details
Product Description
– 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor, but does not appear to function as an agonist.
Web ID
– T38087
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H32O5
CAS Number
– 79516-82-8
Molecular Weight
– C20H32O5
SMILES
– OCCCCCC=C/C[C@@H](O)C=CC=CC=C/[C@@H](O)CCCC(O)=O
Pathway
– Others
Product type
– Small Compound
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