(±)8,9-DiHETE

SKU T37229-25 μg Category Brand:

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Products Details

Product Description

– (±)8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid .[1] It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases. Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.[2]

Web ID

– T37229

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H32O4

References

– VanRollins, M., Frade, P.D., and Carretero, O.A. Oxidation of 5,8,11,14,17-eicosapentaenoic acid by hepatic and renal microsomes. Biochimica et Biophysica Acta 996, 133-149 (1988).

CAS Number

– 867350-87-6

Molecular Weight

– C20H32O4

SMILES

– CCC=C/CC=C/CC=C/CC(O)C(O)CC=C/CCCC(O)=O

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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