12(S)-HETE

SKU T37047-10 μg Category Brand:

1,027 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– 12(S)-HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor)-mediated mechanisms. 12(S)-HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.

Web ID

– T37047

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H32O3

References

– Hamberg, M., and Samuelsson, B. Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc. Natl. Acad. Sci. U.S.A. 71(9), 3400-3404 (1974).

CAS Number

– 54397-83-0

Molecular Weight

– C20H32O3

SMILES

– C([C@H](C/C=CCCCCC)O)=C/C=CC/C=CCCCC(O)=O

Pathway

– MAPK|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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