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Products Details
Product Description
– BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). It is selective for EGFR over other tyrosine and serine/threonine kinases, and cellular studies show that BPIQ-II can selectively inhibit EGF-stimulated signal transmission by competitively binding at the ATP site of EGFR.
Web ID
– T36783
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H11BrClN5
CAS Number
– 171179-37-6
Molecular Weight
– C15H11BrClN5
SMILES
– Cl.BrC1=CC=CC(=C1)NC2=NC=NC3=CC=4N=CNC4C=C32
Pathway
– Others
Product type
– Small Compound
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