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Products Details
Product Description
– TEI-9648, an analogue of Vitamin D3 Lactone, acts as a potent and specific antagonist to the vitamin D receptor (VDR). This compound effectively blocks the genomic actions mediated by VDR and the Vitamin D responsive element (VDRE) of 1α,25(OH)2D3. Furthermore, TEI-9648 prevents the differentiation of HL-60 cells induced by 1α,25(OH)2D3, indicating its utility in bone metabolism studies[1][2].
Web ID
– T36593
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H38O4
References
– Miura D, et al. Antagonistic action of novel 1α,25-dihydroxyvitamin D3-26, 23-lactone analogs on differentiation of human leukemia cells (HL-60) induced by 1α,25-dihydroxyvitamin D3. J Biol Chem. 1999 Jun 4;274(23):16392-9.
CAS Number
– 173388-21-1
Molecular Weight
– C27H38O4
SMILES
– [H][C@@]12CC[C@H]([C@H](C)C[C@@H]3CC(=C)C(=O)O3)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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