(3S)-hydroxy Quinidine

SKU T36561-1 mg Category Brand:

Price range: 757 CAD through 1,437 CAD

Products Details

Product Description

– (3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.

Web ID

– T36561

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H24N2O3

CAS Number

– 53467-23-5

Molecular Weight

– C20H24N2O3

SMILES

– [C@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@@]3([N@@]4C[C@@](C=C)(O)[C@](C3)(CC4)[H])[H]

Target

– Others

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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