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Product Description
– Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid . In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation. The activity of 12(R)-HETE in mammals is predominantly proinflammatory. 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.
Web ID
– T36145
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H32O3
CAS Number
– 82337-46-0
Molecular Weight
– C20H32O3
SMILES
– C([C@@H](C/C=CCCCCC)O)=C/C=CC/C=CCCCC(O)=O
Pathway
– Others
Product type
– Small Compound
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