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6,9-Dichloro-1,2,3,4-tetrahydroacridine

SKU T35975-25 mg Category Brand:

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Products Details

Product Description

– 6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3

Web ID

– T35975

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H11Cl2N

References

– Recanatini, M., Cavalli, A., Belluti, F., et al.SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: Synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analoguesJ. Med. Chem.43(10)2007-2018(2000)

CAS Number

– 5396-25-8

Molecular Weight

– C13H11Cl2N

SMILES

– Clc1ccc2c(Cl)c3CCCCc3nc2c1

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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