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IKD-8344
2,075 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species with diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties [1,2,3]. It is cytotoxic to L5178Y murine leukemia cells (IC50 = 0.54 ng/ml) [1], inhibits growth of the mycelial form of C. albicans (MIC = 6.25 μg/ml), and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia [2,3]. Additionally, it is active against T. spiralis in vitro and in vivo [1].
Web ID
– T35742
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C48H76O12
References
– Minami, Y., Yoshida, K., Azuma, R., et al. Structure of a novel macrodiolide antibiotic IKD-8344. Tetrahedron Lett. 33(48), 7373-7376 (1992).
CAS Number
– 129046-69-1
Molecular Weight
– C48H76O12
SMILES
– [H][C@@]12CC[C@]([H])(O1)[C@H](C)C(=O)O[C@]([H])(C[C@]1([H])CC[C@@]([H])(O1)[C@@H](C)C(=O)C[C@]1([H])CC[C@]([H])(O1)[C@H](C)C(=O)O[C@]([H])(C[C@]1([H])CC[C@@]([H])(O1)[C@@H](C)C(=O)C2)[C@@H](C)[C@]1([H])CC[C@@H](C)O1)[C@@H](C)[C@]1([H])CC[C@@H](C)O1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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