TPX-0046

SKU T35384-1 mg Category Brand:

Price range: 253 CAD through 3,168 CAD

Products Details

Product Description

– TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib.

Web ID

– T35384

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H21FN6O3

References

– Repetto M, et al. The return of RET GateKeeper mutations? an in-silico exploratory analysis of potential resistance mechanisms to novel RET macrocyclic inhibitor TPX-0046. Invest New Drugs. 2022 May 25.

CAS Number

– 2359650-19-2

Molecular Weight

– C21H21FN6O3

Compound Purity

– 0.9995

SMILES

– FC=1C=C2CN3C=4C(=CN5C(N4)=C(C=N5)C(=O)NC[C@@H](C)OC2=NC1)O[C@]6([C@@]3(CCC6)[H])[H]

Target

– Others

Pathway

– Apoptosis|||Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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