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RO8994
Price range: 54 CAD through 910 CAD
Products Details
Product Description
– RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays).
Web ID
– T3517
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H31Cl2FN4O4
References
– Zhang Z,et al. Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy. Bioorg Med Chem. 2014 Aug 1;22(15):4001-9.
CAS Number
– 1309684-94-3
Molecular Weight
– C31H31Cl2FN4O4
Compound Purity
– 0.9944
SMILES
– COc1cc(ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21)C(N)=O
Target
– Others
Pathway
– Ubiquitination|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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