FTIDC
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FTIDC

SKU T3483-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 171 CAD through 1,904 CAD

Products Details

Product Description

– FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.

Web ID

– T3483

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H23FN6O

References

– Ito S, et al. Discovery and biological profile of 4-(1-aryltriazol-4-yl)-tetrahydropyridines as an orally active new class of metabotropic glutamate receptor 1 antagonist. Bioorg Med Chem. 2008 Nov 15;16(22):9817-29.

CAS Number

– 873551-53-2

Molecular Weight

– C18H23FN6O

Compound Purity

– 0.9458

SMILES

– CC(C)N(C)C(=O)N1CCC(=CC1)c1nnn(c1C)-c1cccnc1F

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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