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Products Details
Product Description
– Terbogrel is an orally available thromboxane A2 receptor antagonist and a thromboxane A2 synthase inhibitor, with both IC50s of about 10 nM.
Web ID
– HY-19189
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C23H27N5O2
References
– [1]Muck S, et al. Effects of terbogrel on platelet function and prostaglandin endoperoxide transfer. Eur J Pharmacol. 1998 Feb 26;344(1):45-8.|[2]Soyka R, et al. Guanidine derivatives as combined thromboxane A2 receptor antagonists and synthase inhibitors. J Med Chem. 1999 Apr 8;42(7):1235-49.
CAS Number
– 149979-74-8
Molecular Weight
– 405.49
SMILES
– O=C(O)CCC/C=C(C1=CC=CC(/N=C(NC#N)/NC(C)(C)C)=C1)/C2=CC=CN=C2
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– TXA2/TP
Pathway
– GPCR/G Protein
Product type
– Reference compound
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