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PBOX-15
Price range: 2,672 CAD through 4,480 CAD
Products Details
Product Description
– PBOX-15 is a novel microtubule-targeting agent that induces apoptosis, upregulates death receptors, and enhances TRAIL-mediated apoptosis in multiple myeloma cells. It also inhibits T cell migration through post-translational modification of tubulin. Pbox-15 induced apoptosis, up-regulated death receptors, and enhanced TRAIL-mediated apoptosis in multiple myeloma cells.
Web ID
– T33892
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H19NO3
References
– Nathwani SM, Greene LM, Butini S, Campiani G, Williams DC, Samali A, Szegezdi E, Zisterer DM. The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells. Int J Oncol. 2016 May 12. doi: 10.3892/ijo.2016.3518. [Epub ahead of print] PubMed PMID: 27176505.
CAS Number
– 354759-10-7
Molecular Weight
– C28H19NO3
SMILES
– O(C(C)=O)C1=C(OC=2C(N3C1=CC=C3)=CC=4C(C2)=CC=CC4)C=5C6=C(C=CC5)C=CC=C6
Target
– Immunology/Inflammation related
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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