NLRP3-IN-2
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NLRP3-IN-2

SKU T3230-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 286 CAD

Products Details

Product Description

– NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.

Web ID

– T3230

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H17ClN2O4S

References

– Baldwin, A., Brough, D., & Freeman, S. (2015). Inhibiting the Inflammasome: A Chemical Perspective. Journal Of Medicinal Chemistry, 59(5), 1691-1710. doi: 10.1021/acs.jmedchem.5b01091

CAS Number

– 16673-34-0

Molecular Weight

– C16H17ClN2O4S

Compound Purity

– 0.9898

SMILES

– COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O

Target

– Others

Pathway

– Immunology/Inflammation|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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