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GLL398
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– GLL398 is an oral selective estrogen receptor down-regulating agent that strongly binds to ERα (IC50 =1.14 nM) and effectively degrades ERα in MCF-7 breast cancer cells (IC50 = 0.21 μM).
Web ID
– T31936
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H23BO4
References
– Liu J, Zheng S, Guo S, Zhang C, Zhong Q, Zhang Q, Ma P, Skripnikova EV, Bratton MR, Wiese TE, Wang G. Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator. ACS Med Chem Lett. 2016 Nov 29;8(1):102-106. doi: 10.1021/acsmedchemlett.6b00410. eCollection 2017 Jan 12. PubMed PMID: 28105283; PubMed Central PMCID: PMC5238461.
CAS Number
– 2077980-83-5
Molecular Weight
– C25H23BO4
SMILES
– C(=C(/CC)C1=CC=CC=C1)(C2=CC=C(B(O)O)C=C2)/C3=CC=C(/C=C/C(O)=O)C=C3
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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