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Products Details
Product Description
– Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9, thereby decreasing inflammatory mediators during simulated cardiopulmonary bypass.
Web ID
– T31877
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H28N6O4
References
– Stevens T, Ekholm K, Gränse M, Lindahl M, Kozma V, Jungar C, Ottosson T, Falk-Håkansson H, Churg A, Wright JL, Lal H, Sanfridson A. AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase. J Pharmacol Exp Ther. 2011 Oct;339(1):313-20. doi: 10.1124/jpet.111.182139. Epub 2011 Jul 26. PubMed PMID: 21791628.
CAS Number
– 208848-19-5
Molecular Weight
– C23H28N6O4
SMILES
– C(C(NC(C(=O)C=1OC(C(C)(C)C)=NN1)C(C)C)=O)N2C(=NC=C(N)C2=O)C3=CC=CC=C3
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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