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Products Details
Product Description
– Nrf2 activator-9 (compound D-36) is an Nrf2 activator that inhibits oxidized low-density lipoprotein (oxLDL) and high glucose (HG)-induced apoptosis in HUVEC cells. Nrf2 activator-9 inhibits oxLDL and HG-induced vascular endothelial cell (VEC) injury and can effectively prevent and treat atherosclerosis[1].
Web ID
– HY-156081
Shipping
– Room temperature
Molecular Formula
– C26H27N5O4
References
– [1]Zhang J, et al. Discovery of marine phidianidine-based Nrf2 activators and their potential against oxLDL- and HG-induced injury in HUVECs. Bioorg Med Chem Lett. 2023 Sep 7;95:129468.. .
Molecular Weight
– 473.52
SMILES
– OC1=CC(/C=C/C(N2CCN(CC2)CC3=NOC(CC4=CNC5=CC=CC=C54)=N3)=O)=CC=C1OC
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Keap1-Nrf2
Pathway
– Apoptosis;NF-κB
Product type
– Reference compound
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