SB 216763
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SB 216763

SKU T3077-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 1,354 CAD

Products Details

Product Description

– SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).

Web ID

– T3077

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H12Cl2N2O2

Citations

– 1. Ruan B, Liu W, Chen P, et al. NVP-BEZ235 inhibits thyroid cancer growth by p53- dependent/independent p21 upregulation. International Journal of Biological Sciences. 2020, 16(4): 682 2. Wu L, Lin W, Liao Q, et al. Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation. Cell Reports. 2020, 33(4): 108327

References

– Coghlan MP, et al. Chem Biol, 2000, 7(10), 793-803.

CAS Number

– 280744-09-4

Molecular Weight

– C19H12Cl2N2O2

Compound Purity

– 0.9961

SMILES

– O=C1C(C=2C=3C(N(C)C2)=CC=CC3)=C(C(=O)N1)C4=C(Cl)C=C(Cl)C=C4

Pathway

– Autophagy|||PI3K/Akt/mTOR signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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