VU6001966
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VU6001966

SKU T29142-5 mg Category Brand:

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Product Description

– VU6001966 is a potent and selective mGlu2 inhibitor (mGlu2 IC50 = 78 nM) and negative allosteric modulator. VU6001966 exhibits excellent central nervous system (CNS) penetration.

Web ID

– T29142

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H15FN4O2

References

– Felts AS, Rodriguez AL, Smith KA, Engers JL, Morrison RD, Byers FW, Blobaum AL, Locuson CW, Chang S, Venable DF, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Emmitte KA. Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2. J Med Chem. 2015 Nov 25;58(22):9027-40. doi: 10.1021/acs.jmedchem.5b01371. Epub 2015 Nov 11. PubMed PMID: 26524606; PubMed Central PMCID: PMC4817271.

CAS Number

– 2009052-76-8

Molecular Weight

– C17H15FN4O2

SMILES

– O(CC1=NN(C)C=C1)C=2C(=CC(C(N)=O)=NC2)C3=CC=C(F)C=C3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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