Ono 1301
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Ono 1301

SKU T28240-25 mg Category Brand:

Price range: 1,227 CAD through 2,784 CAD

Products Details

Product Description

– Ono 1301 is a prostaglandin I2 mimetic coumpound with inhibitory activity against thromboxane A2 synthase. Ono 1301 suppresses pancreatic fibrosis in the DBTC-induced CP model by inhibiting monocyte activity not only with induction of HGF but also by Ono 1301 itself. It also works through promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.

Web ID

– T28240

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H24N2O4

References

– Kashiwagi H, Yuhki K, Kojima F, Kumei S, Takahata O, Sakai Y, Narumiya S, Ushikubi F. The novel prostaglandin I2 mimetic ONO-1301 escapes desensitization in an antiplatelet effect due to its inhibitory action on thromboxane A2 synthesis in mice. J Pharmacol Exp Ther. 2015 May;353(2):269-78. doi: 10.1124/jpet.115.222612. Epub 2015 Mar 4. PubMed PMID: 25740898.

CAS Number

– 176391-41-6

Molecular Weight

– C26H24N2O4

SMILES

– C(CO/N=C(C1=CC=CC=C1)/C=2C=CC=NC2)C=3C=4C(=C(OCC(O)=O)C=CC4)CCC3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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