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ML375
Price range: 1,888 CAD through 3,728 CAD
Products Details
Product Description
– ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).
Web ID
– T28068
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H15ClF2N2O2
References
– McGowan KM, Nance KD, Cho HP, Bridges TM, Jeffrey Conn P, Jones CK, Lindsley CW. Continued optimization of the M(5) NAM ML375: Discovery of VU6008667, an M(5) NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359. doi: 10.1016/j.bmcl.2017.02.020. PubMed PMID: 28237763.
CAS Number
– 1488362-55-5
Molecular Weight
– C23H15ClF2N2O2
SMILES
– Fc1ccc(cc1F)C(=O)N1CCN2C(=O)c3ccccc3[C@@]12c1ccc(Cl)cc1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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