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Product Description
– Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2). It exhibits an EC50 of 33 nM and a Ki of 2.4 μM when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-β/Smad2 signaling pathway [1] [2] [3].
Web ID
– T26925
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H40O5
References
– Nilsson SF, Drecoll E, Lütjen-Drecoll E, Toris CB, Krauss AH, Kharlamb A, Nieves A, Guerra T, Woodward DF. The prostanoid EP2 receptor agonist butaprost increases uveoscleral outflow in the cynomolgus monkey. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):4042-9. PubMed PMID: 16936121.
CAS Number
– 69685-22-9
Molecular Weight
– C24H40O5
SMILES
– [C@@H](C/C=C/[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O)(O)C2(CCC)CCC2
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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