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(E)-Daporinad
Price range: 58 CAD through 1,968 CAD
Products Details
Product Description
– (E)-Daporinad (FK866) is a highly specific, non-competitive small molecule inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with potential anti-tumor and anti-angiogenic activities with an IC50 value of 0.09 nM.
Web ID
– T2644
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H29N3O2
Citations
– 1. Xu B, Zhang P, Tang X, et al. Metabolic Rewiring of Kynurenine Pathway during Hepatic Ischemia–Reperfusion Injury Exacerbates Liver Damage by Impairing NAD Homeostasis. Advanced Science. 2022: 2204697.
2. Liu H Y, Wang F H, Liang J M, et al. Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer. Journal of Cancer Research and Clinical Oncology. 2022: 1-14
References
– Nahimana A, et al. Blood, 2009, 113(14), 3276-3286.
CAS Number
– 658084-64-1
Molecular Weight
– C24H29N3O2
Compound Purity
– 0.9944
SMILES
– C(=O)(N1CCC(CCCCNC(/C=C/C=2C=CC=NC2)=O)CC1)C3=CC=CC=C3
Pathway
– Autophagy|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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