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CRT-0105446
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.
Web ID
– T23916
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H18F3N3O2S
References
– Mardilovich K, Baugh M, Crighton D, Kowalczyk D, Gabrielsen M, Munro J, Croft DR, Lourenco F, James D, Kalna G, McGarry L, Rath O, Shanks E, Garnett MJ, McDermott U, Brookfield J, Charles M, Hammonds T, Olson MF. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation. Oncotarget. 2015 Nov 17;6(36):38469-86. doi: 10.18632/oncotarget.6288. PubMed PMID: 26540348; PubMed Central PMCID: PMC4770715.
CAS Number
– 1661846-05-4
Molecular Weight
– C20H18F3N3O2S
SMILES
– C(F)(F)(F)C1=C(C=2C(=CC=NC2)C=3SC(NC(C(C)C)=O)=NC3)C=CC(OC)=C1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
