Pomalidomide
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Pomalidomide

SKU T2384-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 83 CAD through 269 CAD

Products Details

Product Description

– Pomalidomide (CC-4047) is an anti-angiogenic and immunomodulatory agent. Pomalidomide is a ligand for the ubiquitin E3 ligase cereblon (CRBN) and is commonly used in the synthesis of PROTAC products.

Web ID

– T2384

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H11N3O4

Citations

– 1. Durbin A D, Wang T, Wimalasena V K, et al. EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified NeuroblastomaEP300 Controls Enhancers and MYCN in Neuroblastoma. Cancer Discovery. 2022-12 (3) P730 2. Li P, Hu X, Fan Z, et al.Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.Journal of Hematology & Oncology.2024, 17(1): 77.

References

– Muller GW, et al. Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1625-30.

CAS Number

– 19171-19-8

Molecular Weight

– C13H11N3O4

Compound Purity

– 0.9926

SMILES

– Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Pathway

– Apoptosis|||PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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