TLR3-IN-1
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TLR3-IN-1

SKU T22698-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 2,864 CAD

Products Details

Product Description

– TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cells.

Web ID

– T22698

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H13ClFNO3S

References

– Cheng K , Wang X , Yin H . Small-Molecule Inhibitors of the TLR3/dsRNA Complex[J]. Journal of the American Chemical Society, 2011, 133(11):p.3764-3767.

CAS Number

– 1279713-77-7

Molecular Weight

– C18H13ClFNO3S

Compound Purity

– 0.9777

SMILES

– OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1sc2cc(F)ccc2c1Cl

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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